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Physicians also may be reluctant to attribute self-harmful or suicidal intent if the patient is too ill to communicate or because of the impact on privacy, insurance coverage, or family relationships.

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In such a scenario, the TFP recommended intraarticular injection of corticosteroids for involvement of 1 or 2 joints (with the dose depending on the size of the joint; evidence B) (see Figure 4 in the original guideline document).

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Five of the 12 resulted in death; six recovered, and in one the outcome is unknown.

When the increased pain sensitivity and cross-tolerance with OAT are considered, adequate pain control will generally necessitate higher doses of opioid analgesic administered at shorter intervals.

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Hyperuricosuria predisposes to the formation of calcium-containing calculi because sodium urate can produce malabsorption of macromolecular inhibitors or can serve as a nidus for the heterogeneous growth of calcium oxalate crystals.

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So it makes sense that anti-inflammatory drugs alter the messaging system and wreak havoc in the fracture healing process.

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Even men who only played an amateur contact sport during their youth may face an increased risk for chronic traumatic encephalopathy CTE, a devastating brain condition that can affect thinking, memory, behavior and mood, Mayo Clinic researchers report.

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