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Because of limited experience in children and no data in HIV-infected children, data are insufficient to recommend these drugs as first-line agents for invasive candidiasis in children ( CIII).

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An isopropylalaninyl monoamidate phenyl monoester prodrug of tenofovir (GS 7340) was prepared, and its in vitro antiviral activity, metabolism, and pharmacokinetics in dogs were determined.

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Additionally, frequent intravitreous injections are impractical for use in most children ( DIII).

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The prozone phenomenon (a weakly reactive or falsely negative) reaction might occur more frequently in HIV-infected persons ( 147).

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Selective serotonin reuptake inhibitors have been used successfully to treat patients with IFN-associated depression, allowing therapy to be continued, and as a pretreatment to prevent its occurrence in high-risk patients.

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The link between reducing drug use and engaging in successful HIV treatment should be encouraged.

HIV therapy continues to leave behind the days when people had to put up with side effects in order to fight the virus.

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Tenofovir DF in highly antiretroviral-experienced patients: results from a 48-week, randomized, double-blind study.

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Ritonavir and lopinavir (Kaletra) is among the most prescribed combination.

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This review summarizes TDF safety during pregnancy, focusing on pregnancy outcomes, congenital anomaly risk, and other potential toxicities on neonates.

Soaring antiretroviral prices, TRIPS and TRIPS flexibilities: a burning issue for antiretroviral treatment scale-up in developing countries".

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Trimethoprim--sulfamethoxazole (TMP-SMZ) dose escalation versus direct rechallenge for Pneumocystis carinii pneumonia prophylaxis in human immunodeficiency virus-infected patients with previous adverse reaction to TMP-SMZ.

TAF STR offers a promising option for initial HIV treatment, with the high barrier to resistance of darunavir, and the potential for improved long-term renal and bone safety with TAF.

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As a second-generation INSTI, dolutegravir works for some people whose virus has developed drug resistance to raltegravir or elvitegravir, depending on the level of resistance.

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The current document combines recommendations for preventing and treating OIs in HIV-exposed and HIV-infected children into one document; it accompanies a similar document on preventing and treating OIs among HIV-infected adults prepared by a separate group of adult HIV and infectious disease specialists.

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VIREAD tablets are for oral administration in strengths of 150, 200, 250, and 300 mg of tenofovir disoproxil fumarate, which are equivalent to 123, 163, 204 and 245 mg of tenofovir disoproxil, respectively.

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These results are consistent with the data generated in MT-2 extract and isolated plasma; however, unlike the MT-2 extract, conversion to the active diphosphate metabolite was readily observed with intact MT-2 cells and PBMCs.

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