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Management of patients with hyponatremia and SCLC should be guided by the knowledge that some patients with SCLC have ectopic production of atrial natriuretic peptide as the cause of their hyponatremia and may need to be managed differently than SIADH.
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Adapted from: Chobanian AV, Bakris GL, Black HR, et al, and the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure; National Heart, Lung, and Blood Institute; National High Blood Pressure Education Program Coordinating Committee.
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David Bruyette, DVM, DACVIM, of VCA West Los Angeles Animal Hospital and an internal medicine specialist with an emphasis on Addison's disease, prefers to start large dogs (over 60 pounds) at half that amount, because their metabolism is slower.
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