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Is leflunomide dangerous? Leflunomide is an effective disease modifying anti-rheumatic drug (DMARD). However, it can cause serious hepatic, haematologic, respiratory, and dermatologic adverse effects. Leflunomide is a potent immunosuppressant, reducing resistance to infection which, when it occurs, can be severe and disseminated.
How does methotrexate work in cancer treatment? Methotrexate is one of a group of chemotherapy drugs called anti metabolites. These stop cells making and repairing DNA. Cancer cells need to make and repair DNA so that they can grow and multiply. It helps normal cells recover and reduces side effects.
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